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Elian Granule
- Development stage
- Unknown
- Lead developer
- Professor Gan Cai
- Modality
- Implantable Devices → Device-based Delivery → Drug Delivery Systems, Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
- Administration
- Oral
01
Overview
Elian Granule is a traditional Chinese medicine (TCM) formulation developed for the treatment of chronic atrophic gastritis (CAG) and precancerous lesions of gastric cancer. It consists of 12 Chinese herbs and was designed based on TCM principles to address spleen-stomach deficiency, phlegm-dampness, heat-toxin, and qi-blood stasis. Clinical studies have shown that Elian Granule significantly improves gastric mucosal atrophy and intestinal metaplasia, alleviates dyspeptic symptoms such as epigastric pain, distension, discomfort, early satiety, heartburn, belching and acid reflux in CAG patients. The granules also enhance quality of life scores for both physical and mental health domains with a favorable safety profile[1][2]. The mechanism is believed to be multi-targeted through modulation of inflammation and improvement in gastric mucosal health.
- Brand names
- Elian Granule
- Other names
- ElianE-Lian
02
Targets
JAK2 (Janus kinase 2)STAT3 (Signal Transducer and Activator of Transcription 3)
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