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estriol + glatiramer acetate
- Development stage
- Unknown
- Lead developer
- Theriva Biologics
- Modality
- Small Molecules
- Administration
- Oral, Injectable
01
Overview
A combination therapy consisting of oral estriol and injectable glatiramer acetate for the treatment of relapsing-remitting multiple sclerosis in women. Estriol is a pregnancy hormone with anti-inflammatory and neuroprotective properties, while glatiramer acetate is an established disease-modifying therapy that modulates immune processes involved in MS pathogenesis. The combination has shown promise in reducing relapse rates compared to glatiramer acetate alone.
02
Targets
ESR2 (ERβ)MHC II (Major histocompatibility complex class II receptor)ESR1 (ERα)
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