Drug intelligence / Profile preview

ferric carboxymaltose + infliximab

Development stage
Unknown
Lead developer
CSL
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Administration
Intravenous
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Overview

This is a combination therapy consisting of ferric carboxymaltose and infliximab, administered sequentially in a single treatment session, primarily for patients with inflammatory bowel disease (IBD) who have iron deficiency anemia or iron-restricted anemia. Ferric carboxymaltose is an intravenous iron replacement product that replenishes depleted iron stores and corrects anemia by providing bioavailable iron for erythropoiesis. Infliximab is a chimeric monoclonal antibody targeting tumor necrosis factor alpha (TNF-α), used to reduce inflammation in autoimmune diseases such as Crohn’s disease and ulcerative colitis. Studies indicate that same-day administration of these agents is safe, effective, improves hematological parameters, and offers cost and time savings compared to separate administrations.

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Targets

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