Drug intelligence / Profile preview

Fufang Bufei Decoction

Development stage
Unknown
Lead developer
Sichuan University
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Fufang Bufei Decoction (FFBF) is a traditional Chinese medicine (TCM) herbal formula being evaluated for the management of postoperative cough and airway recovery in patients undergoing lung cancer surgery. In clinical studies conducted at the West China Hospital of Sichuan University, the decoction has demonstrated the potential to provide early symptomatic relief of postoperative cough on the day of discharge and reduce hospitalization costs following thoracic surgery.

Other names
FFBF decoctionFuFang-BuFei decoction
02

Targets

IL-6 (Interleukin 6)JAK1 (Janus kinase 1)NFKB1 (NF-κB1)STAT3 (Signal Transducer and Activator of Transcription 3)TLR4 (Toll-like receptor 4)

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