Drug intelligence / Profile preview

Glycosylated rituximab

Development stage
Preclinical
Lead developer
IDEC
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

Glycosylated rituximab is an anti-CD20 monoclonal antibody developed by Fountain Biopharma. It is designed as a biosimilar or biobetter version of rituximab, featuring engineered glycosylation patterns intended to alter or enhance its effector functions, such as antibody-dependent cellular cytotoxicity (ADCC). The drug targets the CD20 antigen expressed on the surface of B cells, leading to their depletion, which is a key therapeutic strategy in managing autoimmune conditions. Its primary development focus is the treatment of Rheumatoid Arthritis.

Other names
glyco-rituximabrituximab biosimilar
02

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