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Inner Mongolia Medical Univ. ROCK2/ROCK1 compound A20

Lead developer: Inner Mongolia Medical University

Overview

Inner Mongolia Medical Univ. ROCK2/ROCK1 compound A20: sourced facts only. name: "compound A20 with a 4-(2-methoxyphenyl)-1H-pyrazole scaffold exhibited superior inhibitory activity against ROCK2 with IC50 value of 0.18 μM and inhibited ROCK1 with IC50 value of 3.0 μM."; target: "compound A20 with a 4-(2-methoxyphenyl)-1H-pyrazole scaffold exhibited superior inhibitory activity against ROCK2 with IC50 value of 0.18 μM and inhibited ROCK1 with IC50 value of 3.0 μM."; target: "compound A20 with a 4-(2-methoxyphenyl)-1H-pyrazole scaffold exhibited superior inhibitory activity against ROCK2 with IC50 value of 0.18 μM and inhibited ROCK1 with IC50 value of 3.0 μM."; developer: "Key Laboratory for Candidate Medicine Design and Screening Based on Chemical Biology, College of Pharmacy, Inner Mongolia Medical University, Hohhot, PR China."

Targets

ROCK1 (Rho-associated coiled-coil containing protein kinase 1)ROCK2 (Rho-associated coiled-coil containing protein kinase 2)

Source types: Peer-reviewed publication. Sources are available to Gosset users. Log in to see them.

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