Drug intelligence / Profile preview

Jianpi Lishi Jiedu formula

Development stage
Unknown
Lead developer
Nanjing Hospital of Integrated Traditional Chinese and Western Medicine
Administration
Oral
01

Overview

Jianpi Lishi Jiedu formula is a Traditional Chinese Medicine (TCM) herbal composition developed by the Nanjing Hospital of Integrated Traditional Chinese and Western Medicine. It is primarily used for the prevention of postoperative recurrence in patients with colorectal adenoma, specifically those diagnosed with the spleen deficiency and dampness-toxin TCM syndrome. The formula's mechanism of action is being investigated for its ability to modulate the IL-6/JAK/STAT3 signaling pathway, which plays a critical role in the inflammatory response and the development of colorectal tumors. By targeting these pathways, the formula aims to inhibit the recurrence of adenomatous polyps following surgical removal.

Other names
Jianpi Lishi Jiedu formula
02

Targets

JAK2 (Janus kinase 2)STAT3 (Signal Transducer and Activator of Transcription 3)IL-6 (Interleukin 6)RORγt

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