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jiawei guizhi longgu oyster decoction
- Development stage
- Unknown
- Lead developer
- Yueyang Hospital of Integrated Traditional Chinese and Western Medicine
- Administration
- Oral
01
Overview
Jiawei Guizhi Longgu Oyster decoction is a modified Traditional Chinese Medicine (TCM) herbal formulation based on the classic 'Guizhi Gancao Longgu Muli Tang'. It is being developed by Yueyang Hospital of Integrated Traditional Chinese and Western Medicine for the treatment of cancer-related insomnia (CRI). The decoction typically contains core ingredients such as Cinnamomi Ramulus (Guizhi), Glycyrrhizae Radix et Rhizoma (Gancao), Fossilia Ossis Mastodi (Longgu), and Ostreae Concha (Muli), with additional herbs ('Jiawei') added to enhance its sedative and spirit-calming effects. In clinical trials, it is evaluated as an adjunctive therapy alongside standard hypnotic treatments to improve sleep quality and reduce the burden of persistent insomnia in adult patients with malignant tumors.
- Other names
- Jiawei Guizhi Longgu Oyster decoctionJiawei Guizhi Longgu Muli TangModified Cinnamon Twig, Fossil Bone and Oyster Shell Decoction
02
Targets
GABRA1 (Gamma-aminobutyric acid type A receptor alpha 1 subunit)5-HT (Serotonin receptors)
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