Drug intelligence / Profile preview

Lanzhou Univ. KRAS G12C compound S32

Development stage
Preclinical
Lead developer
Lanzhou University
01

Overview

Lanzhou Univ. KRAS G12C compound S32: sourced facts only. name: "These results confirmed that S32, with a benzisothiazole scaffold, was an effective KRAS G12C inhibitor, potentially promoting cancer therapy development." [PMID:42863233]; target: "These results confirmed that S32, with a benzisothiazole scaffold, was an effective KRAS G12C inhibitor, potentially promoting cancer therapy development." [PMID:42863233]; developer: "School of Pharmacy, and State Key Laboratory of Natural Product Chemistry, Lanzhou University, Lanzhou 730000, China." [PMID:42863233]; stage: "Furthermore, S32 achieved a tumor growth inhibition (TGI) of 90.8% at a dose of 30 mg/kg." [PMID:42863233]

02

Targets

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