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LRDR
- Development stage
- Preclinical
- Lead developer
- Realize Therapeutics
- Modality
- Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
LRDR is a proprietary probiotic strain of *Lactobacillus reuteri* developed by Realize Therapeutics. It is classified as a live biotherapeutic product (LBP) intended for microbiome restoration and modulation. The primary mechanism involves the restoration of *L. reuteri* as a keystone species in the gut microbiome, which in turn stimulates the natural production of oxytocin and supports intestinal barrier integrity. Realize Therapeutics is exploring the strain for therapeutic applications in gut disorders such as Small Intestinal Bacterial Overgrowth (SIBO) and endotoxemia. While marketed commercially as the dietary supplement MyReuteri, the company maintains a development platform for clinical indications.
- Brand names
- MyReuteriOxiceuticsAdiponexin
- Other names
- Lactobacillus reuteri LRDRL. reuteri LRDR
02
Targets
Oxytocin receptor
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