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LVIVO-TaVec100
- Development stage
- Phase 1
- Lead developer
- Legend Biotech
- Modality
- CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
- Administration
- Intravenous
01
Overview
**LVIVO-TaVec100** is an investigational in vivo CAR-T cell therapy under Phase 1 clinical study for adults with relapsed or refractory B-cell malignancies, including chronic lymphocytic leukemia and non-Hodgkin's lymphoma. Unlike traditional ex vivo CAR-T therapies that require collection and modification of a patient's T cells outside the body, in vivo CAR-T therapies aim to generate CAR-expressing T cells directly within the patient. The mechanism, target antigen, and vector used in LVIVO-TaVec100 have not been publicly disclosed as of date. This therapy is being evaluated for safety, tolerability, and efficacy in a single-dose regimen in human subjects[1][2][4][7].
- Brand names
- LVIVO-TaVec100LVIVO-TaVec-100LVIVO-TaVec 100
- Other names
- LVIVO-TaVec100LVIVO-TaVec-100LVIVO-TaVec 100
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