MAB-anti-CD11

MAB-anti-CD11 is a monoclonal antibody currently in preclinical development by MAB DESIGNS. It is designed to target CD11, which represents the alpha subunit of the beta-2 integrin family (including CD11a, CD11b, CD11c, and CD11d). These proteins are primarily expressed on the surface of various leukocytes and are essential for cell-cell adhesion, transendothelial migration, and immunological synapse formation. By binding to CD11, the antibody is intended to inhibit the interaction between leukocytes and their ligands (such as ICAM-1), thereby modulating inflammatory responses and leukocyte recruitment to tissues. While specific indications have not been disclosed, the mechanism is typically explored for the treatment of autoimmune and inflammatory disorders.

Other names

anti-CD11 monoclonal antibodyanti-CD-11 monoclonal antibodyanti-CD 11 monoclonal antibodyCD11 monoclonal antibodyCD-11 monoclonal antibodyCD 11 monoclonal antibodyanti-CD11anti-CD-11anti-CD 11