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MDMA analog
- Development stage
- Preclinical
- Lead developer
- EQUULUS Therapeutics
- Modality
- Small Molecules
- Administration
- Oral, Sublingual, Intranasal, Intravenous, Subcutaneous
01
Overview
MDMA analog is a small molecule serotonin (5-HT) releaser being developed by EQUULUS Therapeutics for the treatment of post-traumatic stress disorder (PTSD). As a psychedelic-inspired therapeutic, it is designed to be non-dissociative and empathy-enhancing, aiming to provide the prosocial and emotional processing benefits of MDMA without the associated neurotoxicity or euphoric effects. The compound is currently in the discovery stage of development and represents a key asset in EQUULUS's mission to develop mainstream CNS therapeutics that address the root causes of psychiatric conditions.
- Other names
- 3,4-methylenedioxymethamphetamine analog
02
Targets
SERT (Sodium-dependent serotonin transporter)NET (Norepinephrine Transporter)DAT (Dopamine plasma membrane transport protein)5-HT2 (5-HT2 receptor family)
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