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MIRX006
- Development stage
- Preclinical
- Lead developer
- PURMX Therapeutics
- Modality
- MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
- Administration
- Systemic (route Not Specified)
01
Overview
MIRX006 is a preclinical-stage microRNA (miRNA) therapeutic being developed by PURMX Therapeutics for the treatment of solid tumors. The drug consists of a miR-3140 mimic delivered via a proprietary second-generation drug delivery system (DDS). miR-3140 is characterized as a tumor-suppressive miRNA that modulates the expression of various genes involved in cancer cell proliferation and survival. By utilizing an advanced second-generation DDS, MIRX006 is designed to overcome stability and delivery challenges associated with first-generation RNA therapeutics, potentially providing improved efficacy and a better pharmacokinetic profile in the treatment of diverse solid malignancies.
- Other names
- miR-3140 miRNAmiR3140 miRNAmiR 3140 miRNA
02
Targets
CDK2 (Cyclin-dependent kinase 2)BRD3 (Bromodomain-containing protein 3)
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