Drug intelligence / Profile preview

OraCAb

Development stage
Unknown
Lead developer
MicroPharm
Modality
Antibody-Based Therapeutics
Administration
Oral
01

Overview

OraCAb is an orally administered polyclonal antibody therapeutic developed by MicroPharm Limited in collaboration with the United Kingdom Health Security Agency (UKHSA) for the treatment of *Clostridioides difficile* infection (CDI). The drug consists of ovine-derived (sheep) polyclonal antibodies that specifically target and neutralize *C. difficile* Toxin A (TcdA) and Toxin B (TcdB) within the gastrointestinal tract. It features a specialized formulation designed to protect the antibodies from gastric and intestinal degradation, ensuring they remain active at the site of toxin production. Unlike traditional antibiotics, OraCAb treats mild to moderate CDI by neutralizing the pathogenic toxins directly without disrupting the commensal gut microbiota, which may help prevent infection recurrence and preserve colonic health.

Brand names
OraCAb
Other names
MicroPharm Clostridioides difficile antibodyovine polyclonal antibody (TcdA/TcdB)
02

Targets

TcdB (Clostridioides difficile large clostridial toxin family)TcdA (Clostridioides difficile toxin A)

Beyond the preview

Go deeper on OraCAb.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on OraCAb.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call