oxytropis falcata bunge

Oxytropis falcata Bunge is a perennial, stemless herb traditionally used in Tibetan and Chinese medicine. It is widely recognized for its **anti-inflammatory**, **analgesic**, **antioxidant**, **antibacterial**, **hemostatic**, and **antitumor** properties. OF is used clinically for conditions such as **fever**, **pain**, **rheumatoid arthritis**, and **eczema**, and is an active component in formulations like Qingpeng Ointment and Qizheng Xiaotong plaster. Key pharmacologically active compounds are **flavonoids**, including isoflavones (e.g., daidzein, maackiain), flavones (e.g., 7-hydroxyflavone, luteolin), naringenin, and chalcones. Mechanistic studies show that extracts of this plant can inhibit proinflammatory cytokine release and downregulate pathways such as HDAC3/NF-κB and JAK1/STAT1, contributing to reduced inflammation and tissue injury in models of atopic dermatitis and pulmonary fibrosis. Additionally, it upregulates SOCS3, an inhibitor of cytokine signaling[1][2][4][5][7].

Other names

oxytropis falcatasickle-shaped oxytropisOFOFE