Drug intelligence / Profile preview

rituximab + gemcitabine + oxaliplatin

Development stage
Unknown
Lead developer
IDEC
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Administration
Intravenous
01

Overview

R-GemOx is a combination chemotherapy regimen consisting of rituximab (a CD20-targeting monoclonal antibody), gemcitabine (an antimetabolite), and oxaliplatin (a platinum analog). This regimen is primarily used for the treatment of relapsed or refractory diffuse large B-cell lymphoma (DLBCL) in patients who are ineligible for autologous stem cell transplantation. The treatment is typically administered in 14-day cycles, with rituximab, gemcitabine, and oxaliplatin all given on day 1 of each cycle.

Brand names
R-GemOx
Other names
R-GemOXGemOx + Rituximab
02

Targets

DNACD20 (B-lymphocyte antigen CD20)RNR (Ribonucleotide reductase)

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