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RO7121932
- Development stage
- Phase 1
- Lead developer
- Genentech
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
RO7121932 is an investigational drug developed for the treatment of multiple sclerosis (MS). It is a CD20 inhibitor designed to target B-lymphocyte antigen CD20, a protein found on the surface of B cells. By inhibiting CD20, RO7121932 aims to modulate the immune system and reduce disease activity in MS. The drug utilizes a novel 'brain shuttle technology' intended to enhance delivery across the blood-brain barrier. Clinical trials are ongoing to assess its safety, tolerability, pharmacokinetics (how it is processed by the body), and pharmacodynamics (its effects on the body) in people with relapsing-remitting MS (RRMS), primary progressive MS (PPMS), and secondary progressive MS (SPMS). **Developers:** Genentech
- Other names
- brain shuttled antibody for multiple sclerosisbrain shuttle antibodybrain shuttle technology
02
Targets
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