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ShotCAR CD20
- Development stage
- Preclinical
- Lead developer
- Hauul Bio
- Modality
- CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
- Administration
- Intravenous
01
Overview
ShotCAR CD20 is a non-viral chimeric antigen receptor (CAR) cell therapy being developed by Hauul Bio for the treatment of hematologic malignancies. Utilizing Hauul Bio's proprietary ShotCAR platform, the therapy involves engineered immune cells that express a recombinant fusion protein CAR designed to recognize and target CD20-positive malignant cells. Unlike conventional CAR-T therapies that rely on viral vectors for gene transduction, the ShotCAR platform introduces independently expressed and purified recombinant CAR proteins directly into immune cells, offering a safer, more cost-effective, and simplified manufacturing process. ShotCAR CD20 is currently in the discovery and research stage of development.
02
Targets
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