Drug intelligence / Profile preview

Shumisheng plant extract

Development stage
Unknown
Lead developer
Shanxi Shumisheng Pharmaceutical
Administration
Oral
01

Overview

Shumisheng plant extract is a botanical drug product derived from the fruit of *Ziziphus jujuba* (Chinese jujube), specifically standardized for its content of cyclic adenosine monophosphate (cAMP). It is primarily utilized in China as an adjuvant therapy for hematological conditions, including chemotherapy-related anemia (CRA), leukopenia, and thrombocytopenia. As a second messenger, cAMP plays a crucial role in various cellular processes; in the context of anemia, it is thought to promote the proliferation and differentiation of hematopoietic stem cells and potentially synergize with erythropoietin (EPO) to stimulate red blood cell production. Clinical studies, such as those conducted at Changzhi People's Hospital, evaluate its efficacy when combined with recombinant human erythropoietin (rhEPO) for managing anemia in patients with non-myeloid malignancies undergoing chemotherapy.

Brand names
Shumisheng
Other names
Ziziphus jujuba extractcAMP plant extractOral cAMP Compound
02

Targets

EPAC1 (Rap guanine nucleotide exchange factor 3)PKA (Cyclic amp-dependent protein kinase)

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