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South China Univ. of Technology XOR/URAT1 compound II15: sourced facts only. name: "Especially, for II15, the IC50 of XOR is 0.006 ± 0.000 μM, superior to that of febuxostat (IC50 = 0.008 ± 0.000 μM), IC50 of URAT1 is 12.90 ± 2.30 μM, superior to that of benzbromarone (IC50 = 27.04 ± 2.55 μM)."; target: "Especially, for II15, the IC50 of XOR is 0.006 ± 0.000 μM, superior to that of febuxostat (IC50 = 0.008 ± 0.000 μM), IC50 of URAT1 is 12.90 ± 2.30 μM, superior to that of benzbromarone (IC50 = 27.04 ± 2.55 μM)."; target: "Especially, for II15, the IC50 of XOR is 0.006 ± 0.000 μM, superior to that of febuxostat (IC50 = 0.008 ± 0.000 μM), IC50 of URAT1 is 12.90 ± 2.30 μM, superior to that of benzbromarone (IC50 = 27.04 ± 2.55 μM)."; developer: "MOE International Joint Research Laboratory on Synthetic Biology and Medicines, School of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China."; stage: "In acute hyperuricemia mouse model, II15 showed significant uric acid lowering effect."
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