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THANK-u Plus
- Development stage
- Unknown
- Lead developer
- CARsgen Therapeutics
- Modality
- Allogeneic CAR-T → CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
- Administration
- Intravenous
01
Overview
THANK-u Plus is an allogeneic CAR-T cell therapy platform developed by CARsgen Therapeutics. It represents an enhanced version of the company's proprietary allogeneic CAR-T technology, designed to address challenges related to NKG2A expression on natural killer (NK) cells. The platform enables the development of off-the-shelf CAR-T therapies that demonstrate sustained expansion and improved antitumor efficacy in the presence of NK cells compared to earlier versions. Therapies developed using the THANK-u Plus platform include BCMA-targeted and dual-targeting CD19/CD20 CAR-T cells, with robust activity against hematologic malignancies such as relapsed/refractory multiple myeloma and plasma cell leukemia[3].
- Brand names
- THANK-u Plus
- Other names
- THANK-u Plus
02
Targets
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