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Wenluotong lotion

Development stage: Unknown
Lead developer: Fengdu County People's Hospital
Administration: Topical

Overview

Wenluotong lotion is a Traditional Chinese Medicine (TCM) topical formulation developed for the treatment of chemotherapy-induced peripheral neuropathy (CIPN). It is typically used as a soak or wash to alleviate symptoms such as numbness, pain, and tingling in the extremities caused by neurotoxic chemotherapy agents like paclitaxel and platinum-based drugs. The formulation is designed to warm the meridians and unblock collaterals (Wen Jing Tong Luo), a principle in TCM aimed at improving local blood circulation and nerve function. It is currently being evaluated in clinical trials, often in combination with other therapies like compound tripeptide injections, to manage peripheral neurotoxicity in cancer patients.

Other names: Wenluotong xiji

Targets

TNFA (Tumor necrosis factor alpha (soluble))

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