Drug intelligence / Profile preview

Xianglian Huazhuo Granules

Development stage: Unknown
Lead developer: Hebei Provincial Hospital of Traditional Chinese Medicine
Administration: Oral

Overview

Xianglian Huazhuo Granules is a Traditional Chinese Medicine (TCM) herbal formulation developed by the Hebei Provincial Hospital of Traditional Chinese Medicine. It is specifically indicated for the treatment of chronic atrophic gastritis (CAG), a condition involving chronic inflammation and mucosal thinning that serves as a precursor to gastric cancer. The granules are intended to "resolve turbidity" (Huazhuo) and alleviate clinical symptoms such as epigastric pain and bloating. The drug is currently being evaluated in clinical trials to assess its efficacy in improving gastric histopathology, including the potential reversal of intestinal metaplasia and dysplasia, with the ultimate goal of blocking the inflammation–carcinoma transformation sequence.

Other names: Xianglian Huazhuo Keli

Targets

ACC (Acetyl-CoA Carboxylase 1)Adapter (Adapter / scaffold proteins)CASP3 (Caspase-3)GPX4 (Glutathione peroxidase 4)HIF1A (Hypoxia-inducible factor 1-alpha)HSP90AB1 (Heat shock protein HSP 90-beta)Interleukin 17 signaling axisIL1B (Interleukin-1 beta)JAK2 (Janus kinase 2)MMP9 (Matrix metalloproteinase-9)NOTCH (Neurogenic locus notch homolog protein 3)SLC40A1 (Ferroportin)SLC7A11 (Cystine-Glutamate Antiporter)STAT3 (Signal Transducer and Activator of Transcription 3)TNFA (Tumor necrosis factor alpha (soluble))

Beyond the preview

Go deeper on Xianglian Huazhuo Granules.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on Xianglian Huazhuo Granules.