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Yiqi Huayu Jiedu

Development stage: Preclinical
Lead developer: Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine
Administration: Oral

Overview

Yiqi Huayu Jiedu is a Traditional Chinese Medicine (TCM) formulation, specifically a "Recipe" or "decoction," whose name translates to "replenishing qi, activating blood, and detoxifying." It is being investigated for its therapeutic effects in various conditions, including acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and gastric cancer. Clinical trials are exploring its use both as a standalone treatment and in combination with conventional Western medicine therapies, such as FLOT chemotherapy for gastric cancer.

Other names: Yiqi Huayu Jiedu decoction

Targets

JAK2 (Janus kinase 2)STAT3 (Signal Transducer and Activator of Transcription 3)JNK (Mitogen-activated protein kinase kinase kinase family)MAPK14 (p38 mitogen-activated protein kinase alpha)TLR4 (Toll-like receptor 4)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)MAPK3 (Mitogen-activated protein kinase 1)

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