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Yiqi Shengjin powder
- Development stage
- Phase 1
- Lead developer
- Beijing Hospital of Traditional Chinese Medicine
- Modality
- Implantable Devices → Device-based Delivery → Drug Delivery Systems, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
- Administration
- Oral
01
Overview
Yiqi Shengjin powder is a traditional Chinese medicine (TCM) herbal formulation used primarily for the treatment of conditions associated with Qi and Yin deficiency syndromes. It is being investigated for its efficacy and safety in patients with abnormal glucose metabolism (including impaired fasting glucose, abnormal glucose tolerance, or type 2 diabetes mellitus) and grade 1-2 essential hypertension[1][4][6]. The mechanism of action is not fully elucidated but may involve modulation of oxidative stress, lipid metabolism, vascular injury markers, and improvement in TCM syndrome integration. Clinical trials are ongoing to assess its impact on blood pressure control as well as secondary outcomes such as oxidative stress index, lipid metabolism index, ambulatory blood pressure monitoring indices, glucose metabolism indices, vascular injury detection indices, aging indicators[1]. The formula is developed within the framework of TCM by institutions such as Beijing Hospital of Traditional Chinese Medicine affiliated with Capital Medical University[1][7].
- Other names
- Yiqi Shengjin powder
02
Targets
JAK1 (Janus kinase 1)MYD88 (Myeloid differentiation primary response protein MyD88)STAT1 (Signal transducer and activator of transcription protein 1)TLR8 (Toll-like receptor 8)
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