Drug intelligence / Profile preview

Yiqi Zengmian Recipe

Development stage
Preclinical
Lead developer
China Academy of Chinese Medical Sciences
Administration
Oral
01

Overview

Yiqi Zengmian Recipe is a traditional Chinese medicine (TCM) herbal compound formula designed to "tonify Qi" (boost vital energy) and enhance immune function. It is used in TCM for various indications including metabolic disorders and as an adjunct in infectious diseases. Preclinical studies have shown that the formula can enhance the translocation of glucose transporter 4 (GLUT4) from the cytoplasm to the plasma membrane in skeletal muscle tissue of diabetic rats, thereby improving insulin sensitivity—a mechanism similar to that of rosiglitazone[1]. The recipe has also been investigated for its potential role in modulating immune responses during infections such as COVID-19[2]. The exact herbal composition may vary by source but typically includes multiple herbs aimed at supporting spleen and lung Qi according to TCM theory.

Brand names
Yiqi Zengmian Recipe
Other names
Yiqi Zengmin formulaYQZMYiqi Zengmai Formula益气增免方
02

Targets

STAT1 (Signal transducer and activator of transcription protein 1)SLC2A4 (Solute carrier family 2 facilitated glucose transporter member 4)TLR8 (Toll-like receptor 8)JAK1 (Janus kinase 1)MYD88 (Myeloid differentiation primary response protein MyD88)

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