Drug intelligence / Profile preview

Zaoren Ningxin

Lead developer
Tasly Pharmaceutical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Zaoren Ningxin (specifically approved as Zaoren Ningxin Dropping Pills, also known during development as Anshen Dropping Pills or TCM0012) is a Class 1.1 innovative Traditional Chinese Medicine (TCM) developed by Tasly in collaboration with Tianjin University of Traditional Chinese Medicine and Zhejiang University. It was approved by China's National Medical Products Administration (NMPA) in June 2026 for the treatment of insomnia associated with the TCM syndrome of heart and liver blood deficiency, particularly sleep-maintenance disturbance characterized by recurrent nocturnal awakenings. The formulation is derived from the clinical experience of National TCM Master Zhang Boli and is a modification of the classical Suanzaoren Decoction, composed of four herbal ingredients: stir-baked Ziziphi Spinosae Semen (炒酸枣仁), Albiziae Flos (合欢花), Notoginseng Folium (三七叶), and Glycyrrhizae Radix et Rhizoma (甘草). In clinical trials, Zaoren Ningxin demonstrated significant efficacy in improving sleep quality, reducing insomnia severity, and ameliorating daytime functional impairment without the typical side effects of chemical sedatives.

Other names
Anshen Dropping PillsZaoren NingxinZaoren Ningxin DiwanZaoren Ningxin Dripping PillsZaoren Ningxin Pills安神滴丸枣仁宁心滴丸枣仁宁心丸
02

Targets

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