Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Human Papillomavirus Type 11 L1 Major Capsid Protein (HPV-11 L1)
- Target
- HPV-11 L1
- Molecular classification
- Viral structural protein, Capsid protein
01
Overview
The Human Papillomavirus Type 11 L1 Major Capsid Protein (HPV-11 L1) is the primary structural component of the HPV-11 viral capsid. It self-assembles into virus-like particles (VLPs) when expressed recombinantly. These VLPs are highly immunogenic and are used in HPV vaccines to induce neutralizing antibodies, providing protection against HPV-11 infection and associated diseases such as genital warts. The L1 protein is not an enzyme or receptor but rather a structural antigen presented to the immune system to elicit a protective response.
- Other names
- HPV11 L1 proteinHPV-11 L1 VLPHPV type 11 major capsid proteinHPV11 capsid protein
02
Mechanism of action
Vaccination with VLPs induces neutralizing antibodies that prevent HPV-11 infection by blocking viral entry into cells.
03
Biological functions
Viral capsid formationAntigen presentationInduction of neutralizing antibodiesVLP formation
04
Disease associations
Genital warts (condyloma acuminata)HPV infectionCervical dysplasiaAnal dysplasia
05
Safety considerations
Rare allergic reactions to vaccine componentsInjection site reactions
06
Interacting drugs
Quadrivalent HPV vaccine (Gardasil)
1 more in the full profile.
07
Biomarkers
Anti-HPV-11 L1 antibody titers (IgG)Neutralizing antibody titers against HPV-11
Beyond the preview
Go deeper on Human Papillomavirus Type 11 L1 Major Capsid Protein (HPV-11 L1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Human Papillomavirus Type 11 L1 Major Capsid Protein (HPV-11 L1).