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Pharmacogenetic study of FcγRIIIa and HER2 genes in relation to trastuzumab treatment of breast cancer

2006-002532-24Phase 4Completed

Sponsor
Newcastle Hospitals NHS Foundation Trust
Start
Apr 2007
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 4, single-arm trial of trastuzumab in breast cancer, sponsored by Newcastle Hospitals NHS Foundation Trust. Primary endpoints: Frequency of HER2 gene polymorphisms and association with HER2 receptor expression and Frequency of FcγRIIIa and related gene polymorphisms and association with response to trastuzumab. Started Apr 2007; status: completed.

02

Drugs

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Conditions

breast cancer

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