Trial intelligence / Profile preview

Lapatinib plus capecitabine versus trastuzumab plus capecitabine in HER2-positive metastatic breast cancer

2008-000673-38Phase 3Completed

Sponsor
Novartis
Start
Nov 2008
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial in HER2-enriched breast cancer (HER2+) comparing Lapatinib plus capecitabine with Trastuzumab plus capecitabine (2 arms). Primary endpoint: Incidence of CNS as site of first relapse. Started Nov 2008; status: completed.

02

Drugs

lapatinibtrastuzumabcapecitabine
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Conditions

HER2-enriched breast cancer (HER2+)

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