Trial intelligence / Profile preview

ORBIT study in active rheumatoid arthritis requiring biologic therapy

2009-011268-13Phase 4Completed

Sponsor
NHS Greater Glasgow and Clyde
Start
Mar 2010
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 4, randomised trial of rituximab, etanercept and adalimumab in rheumatoid arthritis (RA) (2 arms), sponsored by NHS Greater Glasgow and Clyde. Primary endpoint: Mean change in Disease Activity Score (DAS28) between baseline and 12 months. Started Mar 2010; status: completed.

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Drugs

rituximabetanerceptadalimumab
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Conditions

rheumatoid arthritis (RA)

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