Trial intelligence / Profile preview

Neoadjuvant lapatinib versus trastuzumab with EC followed by paclitaxel in HER2-positive breast cancer

2010-018389-22Phase 2Completed

Sponsor
GSK
Start
Aug 2010
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of lapatinib, trastuzumab, epirubicin, cyclophosphamide and paclitaxel in breast cancer (2 arms), sponsored by GSK. Primary endpoint: Pathologic complete response in the breast. Started Aug 2010; status: completed.

02

Drugs

lapatinibtrastuzumabepirubicincyclophosphamidepaclitaxel
03

Conditions

breast cancer

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