Trial intelligence / Profile preview

Tocilizumab versus adalimumab plus methotrexate in rheumatoid arthritis after inadequate response to one TNF inhibitor

2010-023587-40Phase 4Completed

Sponsor
Roche
Start
Feb 2011
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, double-blind trial in rheumatoid arthritis (RA) comparing Tocilizumab + methotrexate with Adalimumab + methotrexate (2 arms). Primary endpoint: Clinical remission at Week 24. Started Feb 2011; status: completed.

02

Drugs

tocilizumabadalimumabmethotrexate
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Conditions

rheumatoid arthritis (RA)

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