Trial intelligence / Profile preview

Certolizumab pegol plus methotrexate versus adalimumab plus methotrexate in adults with rheumatoid arthritis inadequately responding to methotrexate

2011-002067-20Phase 4Completed

Sponsor
UCB
Start
Feb 2012
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, single-blind trial in rheumatoid arthritis (RA) comparing Certolizumab pegol plus methotrexate with Adalimumab plus methotrexate (2 arms). Primary endpoints: Percentage of subjects meeting ACR20 criteria and Week 12 prediction of Week 104 treatment success. Started Feb 2012; status: completed.

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Drugs

certolizumab pegoladalimumabmethotrexate
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Conditions

rheumatoid arthritis (RA)

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