Trial intelligence / Profile preview

Lapatinib combinations in trastuzumab-resistant HER2-positive metastatic breast cancer

2012-000598-22Phase 2Terminated

Sponsor
BNGO
Start
Feb 2013
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial in breast cancer comparing Tyverb + trastuzumab with Tyverb + capecitabine (2 arms). Primary endpoint: 6-month progression-free survival rate. Started Feb 2013; status: terminated.

02

Drugs

lapatinibtrastuzumabcapecitabine
03

Conditions

breast cancer

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