Trial intelligence / Profile preview

Feasibility of chemoradiation with trastuzumab and pertuzumab in resectable HER2-positive esophageal carcinoma

2013-004111-42Phase 2Completed

Sponsor
Academic Medical Center
Start
Jan 2014
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of trastuzumab, pertuzumab, carboplatin and paclitaxel in esophageal adenocarcinoma (EAC), gastroesophageal junction adenocarcinoma and esophageal cancer, sponsored by Academic Medical Center. Primary endpoint: Feasibility of preoperative treatment. Started Jan 2014; status: completed.

02

Drugs

trastuzumabpertuzumabcarboplatinpaclitaxel
03

Conditions

esophageal adenocarcinoma (EAC)gastroesophageal junction adenocarcinomaesophageal cancer

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