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INTEGA trial of nivolumab + trastuzumab with ipilimumab or FOLFOX in untreated HER2-positive esophagogastric adenocarcinoma

2017-000624-10Phase 2Completed

Sponsor
AIO-Studien
Start
Jul 2017
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of nivolumab, trastuzumab, ipilimumab, oxaliplatin, fluorouracil and 1 more in gastroesophageal junction adenocarcinoma and gastric cancer (GC) (2 arms), sponsored by AIO-Studien. Primary endpoints: Overall survival and 12-month overall survival milestone rate. Started Jul 2017; status: completed.

02

Drugs

nivolumabtrastuzumabipilimumaboxaliplatinfluorouracil
03

Conditions

gastroesophageal junction adenocarcinomagastric cancer (GC)

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