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Neoadjuvant palbociclib + letrozole + trastuzumab/pertuzumab versus paclitaxel + trastuzumab/pertuzumab in ER-positive/HER2-positive early breast cancer

2017-005067-40Phase 2Completed

Sponsor
ETOP IBCSG Partners Foundation
Start
Aug 2018
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial in breast cancer comparing Palbociclib + letrozole + trastuzumab + pertuzumab with Paclitaxel + trastuzumab + pertuzumab (2 arms). Primary endpoint: Pathological complete response. Started Aug 2018; status: completed.

02

Drugs

palbociclibletrozolepaclitaxeltrastuzumabpertuzumab
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Conditions

breast cancer

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