Trial intelligence / Profile preview

Breast Immune Selection (BIS) preoperative randomized trial in early breast cancer

2020-004696-41Phase 2Active

Sponsor
Gustave Roussy
Start
Jul 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Small Molecules
Countries
1
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Overview

Phase 2, randomised trial of atezolizumab, bevacizumab, ipatasertib, pertuzumab and trastuzumab in breast cancer and triple-negative breast cancer (TNBC) (5 arms), sponsored by Gustave Roussy. Primary endpoints: Immune activation in paired samples and Tumor immunogenicity ratios. Started Jul 2021; status: active.

02

Drugs

atezolizumabbevacizumabipatasertibpertuzumabtrastuzumab
03

Conditions

breast cancertriple-negative breast cancer (TNBC)

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