Trial intelligence / Profile preview

Phase II Study of Neratinib and Trastuzumab with or without oral Vinorelbine in HER2-positive metastatic breast cancer

2022-002582-15Phase 2Terminated

Sponsor
Medical University of Graz
Start
Mar 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of neratinib, trastuzumab and vinorelbine in HER2-enriched breast cancer (HER2+) (2 arms), sponsored by Medical University of Graz. Primary endpoint: Progression-free survival at 6 months. Started Mar 2023; status: terminated.

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Drugs

neratinibtrastuzumabvinorelbine
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Conditions

HER2-enriched breast cancer (HER2+)

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