Trial intelligence / Profile preview

DESTINY-Breast09 first-line HER2-positive metastatic breast cancer study

2023-505249-24-00Phase 3Authorised

Sponsor
AstraZeneca
Start
May 2021
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
25
01

Overview

Phase 3, randomised trial of trastuzumab deruxtecan, pertuzumab, trastuzumab, paclitaxel and docetaxel in breast cancer (3 arms), sponsored by AstraZeneca. Primary endpoint: Progression-free survival by BICR. Planned start May 2021; status: authorised.

02

Drugs

trastuzumab deruxtecanpertuzumabtrastuzumabpaclitaxeldocetaxel
03

Conditions

breast cancer

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