Trial intelligence / Profile preview

EVIDENT in metastatic colorectal cancer

2023-510092-62-00Phase 2Authorised

Sponsor
Oslo University Hospital
Start
May 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of methotrexate, trastuzumab, alectinib, everolimus, talazoparib and 10 more in colorectal cancer (CRC) (15 cohorts), sponsored by Oslo University Hospital. Primary endpoints: Pre-screening feasibility of profiling and organoid establishment and Objective response rate. Planned start May 2024; status: authorised.

02

Drugs

methotrexatetrastuzumabalectinibeverolimustalazoparib
03

Conditions

colorectal cancer (CRC)

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