Trial intelligence / Profile preview

PRIMERA trial in newly diagnosed rheumatoid arthritis

2024-511530-12-01Phase 4Completed

Sponsor
Erasmus MC
Start
Oct 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised, open-label trial of methotrexate, filgotinib, golimumab, adalimumab, etanercept and 7 more in rheumatoid arthritis (RA) (2 arms), sponsored by Erasmus MC. Primary endpoints: Proportion of patients using a biologic or targeted synthetic DMARD after 10 months, Disease activity score over time and 1 more. Started Oct 2024; status: completed.

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Drugs

methotrexatefilgotinibgolimumabadalimumabetanercept
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Conditions

rheumatoid arthritis (RA)

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