Trial intelligence / Profile preview

ARTEMIDE-Gastric01 first-line HER2-positive gastric cancer study

2024-512583-57-00Phase 3Authorised

Sponsor
AstraZeneca
Start
Jul 2025
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
27
01

Overview

Phase 3, randomised trial of rilvegostomig, trastuzumab deruxtecan, pembrolizumab, trastuzumab, fluorouracil and 3 more in gastric adenocarcinoma and gastroesophageal junction adenocarcinoma (2 arms), sponsored by AstraZeneca. Primary endpoints: Progression-free survival and Overall survival. Planned start Jul 2025; status: authorised.

02

Drugs

rilvegostomigtrastuzumab deruxtecanpembrolizumabtrastuzumabfluorouracil
03

Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinoma

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Study design & results

Available in the Gosset platform where reported.

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