Trial intelligence / Profile preview

PHERFLOT perioperative pembrolizumab + trastuzumab + FLOT for HER2-positive localized esophagogastric adenocarcinoma

2024-513610-34-00Phase 2Completed

Sponsor
Institut für Klinische Krebsforschung
Start
Oct 2024
Modality
Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of pembrolizumab, trastuzumab, docetaxel, oxaliplatin, folinic acid and 1 more in gastroesophageal junction adenocarcinoma and gastric adenocarcinoma, sponsored by Institut für Klinische Krebsforschung. Primary endpoints: Disease-free survival and Pathological complete response rate. Started Oct 2024; status: completed.

02

Drugs

pembrolizumabtrastuzumabdocetaxeloxaliplatinfolinic acid
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Conditions

gastroesophageal junction adenocarcinomagastric adenocarcinoma

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Available in the Gosset platform where reported.

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