Trial intelligence / Profile preview

Adalimumab combination therapy in Crohn's disease: azathioprine versus methotrexate

2024-514633-38-00Phase 3Authorised

Sponsor
CHU Amiens-Picardie
Start
Aug 2024
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial in Crohn's disease comparing Adalimumab + azathioprine with Adalimumab + methotrexate (2 arms). Primary endpoint: Endoscopic response at week 26. Planned start Aug 2024; status: authorised.

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Drugs

adalimumabazathioprinemethotrexate
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Conditions

Crohn's disease

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