Trial intelligence / Profile preview

MITHRIDATE first-line treatment trial in high-risk polycythemia vera

2024-516109-21-00Phase 3Authorised

Sponsor
University of Birmingham
Start
Dec 2024
Modality
Small Molecules, Cytokines & Interferons → Recombinant Proteins and Enzymes, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
2
01

Overview

Phase 3, randomised, open-label trial in polycythemia vera (PV) comparing Ruxolitinib, Hydroxycarbamide and Peginterferon alfa-2a (3 arms). Primary endpoint: Event-free survival. Planned start Dec 2024; status: authorised.

02

Drugs

ruxolitinibhydroxyureainterferon alfa
03

Conditions

polycythemia vera (PV)

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