Trial intelligence / Profile preview

COMMIT-CD: Mirikizumab With or Without Tirzepatide in Crohn’s Disease and Obesity/Overweight

2024-520210-21-00Phase 3Authorised

Sponsor
Eli Lilly and Company
Start
Aug 2025
Modality
Recombinant Proteins and Enzymes, Peptides, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
21
01

Overview

Phase 3, randomised, double-blind trial in Crohn's disease, obesity and Overweight comparing Mirikizumab + Tirzepatide with Mirikizumab + Placebo (2 arms). Primary endpoint: Composite clinical and endoscopic remission with weight reduction. Planned start Aug 2025; status: authorised.

02

Drugs

mirikizumabtirzepatide
03

Conditions

Crohn's diseaseobesityOverweight

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