Trial intelligence / Profile preview

SYNERGY-Outcomes master protocol in high-risk MASLD

2025-522674-36-00Phase 3Authorised

Sponsor
Eli Lilly and Company
Start
Mar 2026
Modality
Recombinant Proteins and Enzymes, Peptides
Countries
33
01

Overview

Phase 3, randomised, double-blind trial of tirzepatide and retatrutide in metabolic dysfunction-associated steatotic liver disease (MASLD) (4 arms), sponsored by Eli Lilly and Company. Primary endpoints: Time to first occurrence of any major adverse liver outcome and Composite major adverse liver outcomes endpoint. Planned start Mar 2026; status: authorised.

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Drugs

03

Conditions

metabolic dysfunction-associated steatotic liver disease (MASLD)

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